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There is an amazing article in last month's Bicycling Magazine about "Team Type 1", professional bikers with diabetes: http://www.bicycling.com/article/0,6610,s1-3-12-17839-1,00.html. Good for us all to read actually.
I myself have some curvatures/degenerative spine issues, but as long as I keep in shape they don't bother me.
I only have one eye, it doesn't have much effect on my riding other than that it sucks trying to look over my right shoulder. I usually try to keep other people on my left side so I can see them when I ride.
Other than that, I have degenerative disk disease... some of the disks in my back are bulging and pretty painful when I sit or stand but that just needs some real good stretching before and after rides to keep much injury from happening.
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